Hi everyone. Have searched through all posts hoping for answer to my question but nothing doing. I have been taking methotrexate for about 4 months and the past 6 weeks I have been under the Doctor for High Blood Pressure and increased Heart Rate. The main worry is the heart rate has been over 100 for the last 4 weeks. Have had chest x rays , full blood counts and am due to have Thyroide blood test on Thursday. I am also short of breath. Cant go up stairs without being out of breath.My liver function was 58 and have gone down this week to 38. The Methorexate is taken by injection 10mg. When I saw the GP yesterday he said it could be to do with the methotrexate or that an inflamation can cause the increased blood pressure and heart rate.. Has anyone else had these symptons. I am seriously thinking of coming off methorexate but need to get as much information before I talk to Rheumy nurses. My next appt is on Thursday which is also the same day as I inject.
Thanks to all those who always answer my posts. I dont know what I would do without this forum
Christine

Hi Chris

As Jenni says it is unlikely to be methotrexate at the root of the problem. The breathlessness could be due to the RA and lung issues. The most likely cause from what you have said is a high level of inflammation causing BP/pulse increase.

Are you on any other drugs apart from methotrexate?

Lyn x

Hi Christine

Yes, it can be confusing at times! Is your RA well controlled on the methotrexate? I wouldn't be in too much of a hurry to come off it if it is in fact controlling the RA for you. It is certainly a well regarded drug and very effective in the treatment of RA. Hope you get more information when you see the nurse and start to feel better soon,

Lyn x